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Evolutionary genomics under sexual and clonal reproduction in hybrid wild grasses at the University of East Anglia
Primary supervisor: Dr. Jose de Vega
Scientific background:
Interspecific hybridization is a common mechanism of diversification in plants, unlike animals, largely because plants can overcome hybrid sterility through chromosome doubling, resulting in polyploid plants. Hybridization and polyploidy lead to widespread genome instability and reprogramming, manifesting as widespread structural and genetic variation, a phenomenon known as “genomic shock.” Apomixis, a form of asexual reproduction by producing clonal seeds, is often found associated with hybridization between species. It is suggested that it is a transitional trait that can act as a “safety net” between hybrid formation and genetic stability.
The evolutionary implications of apomixis remain unresolved despite their widespread distribution in all major plant groups (spanning over 300 genera): while heterozygous asexual lineages can benefit from stable heterozygosity, potential heterozygosity, and the maintenance of well-adapted genotypes, they lack the genetic recombination necessary for adaptive evolution through natural selection.
This project aims to study how heterosexual reproduction affects genetic diversity, regulatory dynamics, and evolutionary adaptability compared to sexual reproduction in natural (wild) plant populations. We will address two questions: (1) Does apomixis function as a post-traumatic transitional “safety net” mechanism that enables hybrid persistence and genome stabilization? (2) Does apomixis restrict the long-term adaptability and evolutionary potential of a lineage?
methodology:
This project will investigate the evolutionary trade-offs of apomixis using transcriptomic and marker-based data, combined with new whole-genome resequencing, from hundreds of closely related sexual, offspring, and hybrid accessions within Urochloa (syn. Brachiaria) species complexes. Analyzes will include population genomics, dose and gene expression analysis, admixture and progression analysis, and analysis of epigenomic and structural variation.
an exercise:
You will develop a wide range of skills in computational biology, genetic analysis, bioinformatics, and scientific writing. You will also gain experience in evolutionary biology, plant sciences and statistics. There is potential to explore basic molecular and horticultural techniques. In addition, you will participate in both external and internal bioinformatics training courses and attend and attend local conferences, symposia, department groups, institutes, and journal clubs.
Person specifications:
We are looking for a highly motivated individual with a strong interest in evolution and genomics and a basic understanding of R or Python.
Entry requirements:
At least a UK BA (Hons) equivalency of 2:1. English language requirements (Faculty of Science equivalent: IELTS 6.5 overall, 6 in each category).
Acceptable first degree: A degree related to biological sciences, environmental sciences or bioinformatics.
Study method: Full or part time
Start date: October 1, 2026
Additional financing information
ARIES Scholarships are governed by UKRITerms and Conditions. Successful candidates who meet UKRI’s eligibility criteria will be awarded a fully-funded scholarship, which covers fees, a maintenance stipend (£20,780 per annum for 2025/26) and a Research Training and Support Grant (RTSG). A limited number of scholarships are available to international applicants, with the difference between ‘national’ and ‘international’ fees waived by the registered university. However, please note that ARIES funding does not cover additional costs associated with moving to and living in the UK, such as visa costs or additional health fees.
https://www.jobs.ac.uk/job/DOZ917/phd-studentship-evolutionary-genomics-under-sexual-and-clonal-reproduction-in-hybrid-wild-grasses/



