Research Fellow in Microfluidics for Bioprocess Formulation at University College London

Research Fellow in Microfluidics for Bioprocess Formulation at University College London
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Research Fellow in Microfluidics for Bioprocess Formulation at University College London

about us

UCL Biochemical Engineering (UCL-BE) is a world leader in bioprocessing, where researchers harness cutting-edge facilities and industrial partnerships to turn breakthroughs in biology into sustainable, real-world innovations, and where exciting careers are being launched. Lonza has been at the forefront of therapeutic protein manufacturing in mammalian cells since the early 1980s and is one of the largest healthcare manufacturing organizations in the world. We are looking for highly motivated researchers to form a team to realize a new paradigm to improve the vital process of autonomous navigation.

About the role

Next-generation biopharmaceuticals are becoming increasingly complex, making them more effective but harder to produce. Delivering such discoveries to patients requires careful evaluation and manufacturing optimization. We have identified an opportunity to combine continuous microfluidic (ÂμF) process models, process analysis technology (PAT) and machine learning (ML) to achieve a paradigm shift in bioprocess optimization across modalities and throughout the process. We will investigate three prototypes for (1) protein aggregation (safety), (2) protein refolding (therapeutic activity), and (3) culture medium optimization (cost-effectiveness). Expected benefits include shorter time to get to the clinic, improved access to life-saving medicines, and enhanced sustainability. The project is co-led by UCL-BE and Lonza, and is funded for three years. This is one of three Research Fellow positions for the Lonza UCL PP team. The post holder, based at UCL-BE, will conduct original experimental research, develop and thoroughly characterize all elements of the Microfluidic Technology theme, while collaborating on the other two themes (PAT, ML). The criterion for success will be the realization of all three models, in close cooperation with Lonza experts. The role also involves ownership of scholarly communication outputs, including reports, operating protocols, presentations and archival journal publications, which are delivered to high professional and academic standards. The position is funded for 24 months in the first instance.

About you

You are a microfluidics enthusiast with a passion for bridging physics/engineering and life sciences, and a desire to apply this passion to industrial challenges. You enjoy team-based problem solving and being an ambassador for your team, presenting your work in ways that are engaging to both artistic and wider audiences. You must have a PhD in a relevant discipline (such as engineering, biotechnology, or natural sciences) or related disciplines, and preferably have experience in one or more of the following areas: microfluidics, microfabrication, systems integration, and life sciences. There will be a high degree of interaction with UCL and Lonza colleagues, therefore excellent teamwork and communication skills are required. For informal enquiries, please contact Professor Nicholas Sze Ta at

What we offer

We also offer some great benefits, visit https://www.ucl.ac.uk/work-at-ucl/rewards-and-benefits To learn more.

Our commitment to equality, diversity and inclusion

As a global university in London, we know that diversity fosters creativity and innovation, and we want our community to represent the diversity of global talent. We are committed to equal opportunity, being fair and inclusive, and being a place where we all belong. We therefore particularly encourage applications from candidates who are likely to be under-represented in the UCL workforce. This includes people from black, Asian and minority ethnic backgrounds; People with disabilities People from the LGBTQI+ community; As for our roles in the ninth and tenth grades, they are for women. Our department has received a Gold Athena Swan Award in recognition of our commitment and demonstrated impact in advancing gender equality. You can read more about our commitment to equality, diversity and inclusion here: https://www.ucl.ac.uk/equality-diversity-inclusion/

https://www.jobs.ac.uk/job/DOZ642/research-fellow-in-microfluidics-for-bioprocess-formulation/

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